Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism
subject: Middle East respiratory syndrome coronavirus, severe acute respiratory syndrome coronavirus, coronavirus spike glycoprotein, vaccine platforms, correlates of immunity, animal models
description: Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines.
creator: Craig Schindewolf, Vineet D. Menachery
source: Viruses
publisher: MDPI AG
date: 2019
language: EN
identifier: DOI: 10.3390/v11010074
coverage: Microbiology