Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)

Quality of life reported by survivors after hospitalization for Middle East respiratory syndrome (MERS)

Sarah Batawi, Nehal Tarazan, Rajaa Al-Raddadi, Eman Al Qasim, Anees Sindi, Sameera AL Johni, Fahad M. Al-Hameed, Yaseen M. Arabi, Timothy M. Uyeki, Basem M. Alraddadi

Abstract Introduction Data are lacking on impact of Middle East Respiratory Syndrome (MERS) on health-related quality of life (HRQoL) among survivors. Methods We conducted a cross-sectional survey of MERS survivors who required hospitalization in Saudi Arabia during 2016–2017, approximately 1 year after diagnosis. The Short-Form General Health Survey 36 (SF-36) was administered by telephone interview to assess 8 quality of life domains for MERS survivors and a sample of survivors of severe acute respiratory infection (SARI) without MERS. We compared mean SF-36 scores of MERS and non-MERS SARI survivors using independent t-test, and compared categorical variables using chi-square test. Adjusted analyses were performed using multiple linear regression. Results Of 355 MERS survivors, 83 were eligible and 78 agreed to participate. MERS survivors were younger than non-MERS SARI survivors (mean ± SD): (44.9 years ±12.9) vs (50.0 years ±13.6), p = 0.031. Intensive care unit (ICU) admissions were similar for MERS and non-MERS SARI survivors (46.2% vs. 57.1%), p = 0.20. After adjusting for potential confounders, there were no significant differences between MERS and non-MERS SARI survivors in physical component or mental component summary scores. MERS ICU survivors scored lower than MERS survivors not admitted to an ICU for physical function (p = 0.05), general health (p = 0.01), vitality (p = 0.03), emotional role (p = 0.03) and physical component summary (p 

2019

health related quality of life (HRQoL), coronavirus, Middle East respiratory syndrome (MERS), Pneumonia, Saudi Arabia, Severe acute respiratory infection (SARI)

DOI: 10.1186/s12955-019-1165-2

Health and Quality of Life Outcomes

BMC

Computer applications to medicine. Medical informatics

EN