https://www.socictopen.socict.org/files/original/8ada9ada705720972fed1da9a1885111.pdf 4a21a252ed9cfd2bfd011a1dd20e6f9e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Evolutionary Implications of the microRNA- and piRNA Complement of <i>Lepidodermella squamata</i> (Gastrotricha) Creator An entity primarily responsible for making the resource Bastian Fromm, Juan Pablo Tosar, Felipe Aguilera, Marc R. Friedländer, Lutz Bachmann, Andreas Hejnol Description An account of the resource Gastrotrichs&#8212;&#8217;hairy bellies&#8217;&#8212;are microscopic free-living animals inhabiting marine and freshwater habitats. Based on morphological and early molecular analyses, gastrotrichs were placed close to nematodes, but recent phylogenomic analyses have suggested their close relationship to flatworms (Platyhelminthes) within Spiralia. Small non-coding RNA data on e.g., microRNAs (miRNAs) and PIWI-interacting RNAs (piRNA) may help to resolve this long-standing question. MiRNAs are short post-transcriptional gene regulators that together with piRNAs play key roles in development. In a &#8216;multi-omics&#8217; approach we here used small-RNA sequencing, available transcriptome and genomic data to unravel the miRNA- and piRNA complements along with the RNAi (RNA interference) protein machinery of Lepidodermella squamata (Gastrotricha, Chaetonotida). We identified 52 miRNA genes representing 35 highly conserved miRNA families specific to Eumetazoa, Bilateria, Protostomia, and Spiralia, respectively, with overall high similarities to platyhelminth miRNA complements. In addition, we found four large piRNA clusters that also resemble flatworm piRNAs but not those earlier described for nematodes. Congruently, transcriptomic annotation revealed that the Lepidodermella protein machinery is highly similar to flatworms, too. Taken together, miRNA, piRNA, and protein data support a close relationship of gastrotrichs and flatworms. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource MicroRNAs, piRNAs, RNAi protein machinery, Gastrotricha, <i>Lepidodermella squamata</i>, Platyhelminthes Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ncrna5010019 Source A related resource from which the described resource is derived Non-Coding RNA Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Genetics Language A language of the resource EN