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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Agricultura sostenible</text>
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            <description>An account of the resource</description>
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                <text>Dominio científico: Agricultura sostenible</text>
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      <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <name>Title</name>
          <description>A name given to the resource</description>
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              <text>From degeneration to infection/inflammation, and from individual-centered to ecologic approaches to investigation of evolving patterns of diseases occurrences in populations Da degeneração à infecção e da abordagem centrada no indivíduo à investigação ecológica dos padrões de ocorrência de enfermidades nas populações</text>
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              <text>Maria Inês Reinert Azambuja</text>
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              <text>Variation in attributes of CHD cases over time suggests a temporal change in the source sub-population of cases. It is proposed that an early 20th century expansion of a CHD-prone sub-population, characterized by high-serum cholesterol phenotype and high case-fatality - and which contributed with most of the CHD cases and deaths during the 1960s - may have followed the 1918 Influenza Pandemic. The extinction of those birth-cohorts would have resulted in a relative increase in cases coming from a second source sub-population, characterized by insulin resistance and chronic expression of low grade inflammation markers, comparatively less vulnerable to acutely die from CHD. This re-interpretation of the CHD trend, and the abandonment of the idea of degeneration for inflammation/infection calls for a change in epidemiology. Besides exposures (diet, infection...), temporal variations in proportional representations of inherited and acquired phenotypes associated with individual resistance/vulnerability, would be important determinants of evolving patterns of diseases occurrences in populations.A variação registrada nos atributos dos casos de Doença Isquêmica do Coração (DIC) ao longo do tempo sugere variação temporal na subpopulação fonte dos casos. Propõe-se que tenha ocorrido, em associação com a Pandemia de Influenza de 1918, a expansão de uma subpopulação caracterizada por um fenótipo de hipercolesterolemia e alta propensão à mortalidade por DIC, que teria contribuído com a maior parte dos casos e dos óbitos por DIC registrados na década de 1960. A progressiva extinção daquelas coortes de nascimento teria resultado em crescimento relativo dos casos de DIC oriundos de uma segunda subpopulação, caracterizada por resistência à insulina e expressão de marcadores associados a inflamação crônica subclínica. Esta re-interpretação da tendência temporal da mortalidade por DIC, e o abandono da idéia de degeneração pela idéia de inflamação/infecção pede por uma mudança na epidemiologia. Além de exposições ambientais (dieta, infecção), variações temporais nas representações proporcionais de fenótipos associados à resistência e à vulnerabilidade individual seriam importantes determinantes dos padrões de ocorrência de doenças em populações.</text>
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              <text>2004</text>
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          <name>Subject</name>
          <description>The topic of the resource</description>
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              <text>Doença cardiovascular, Ecologic studies, Epidemia, Epidemic, Mortalidade, ecología humana, heart disease, influenza, mortality</text>
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          <name>Identifier</name>
          <description>An unambiguous reference to the resource within a given context</description>
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              <text>10.1590/S1413-81232004000400007</text>
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          <name>Source</name>
          <description>A related resource from which the described resource is derived</description>
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              <text>Ciência &amp; Saúde Coletiva</text>
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          <name>Publisher</name>
          <description>An entity responsible for making the resource available</description>
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              <text>Associação Brasileira de Pós-Graduação em Saúde Coletiva</text>
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          <name>Coverage</name>
          <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <text>Public aspects of medicine</text>
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          <description>A related resource</description>
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              <text>&lt;a href="http://www.scielo.br/scielo.php?script=sci_arttext&amp;amp;pid=S1413-81232004000400007" target="_blank" rel="noreferrer noopener"&gt;http://www.scielo.br/scielo.php?script=sci_arttext&amp;amp;pid=S1413-81232004000400007&lt;/a&gt;</text>
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