CORONAVIRUS DISEASE (COVID-19) TREATMENT ALGORITHMS IN PATIENTS WITH QT INTERVAL PROLONGATION

CORONAVIRUS DISEASE (COVID-19) TREATMENT ALGORITHMS IN PATIENTS WITH QT INTERVAL PROLONGATION

Snezhitskiy V. A., Kalatsei L. V., Ardashev A. V.

Since the frst cases of coronavirus disease (COVID-19) have been identifed, the search for effective drugs forits treatment has not stopped. The most promising in the treatment of COVID-19 are antimalarial, antiretroviraldrugs and macrolide antibiotics. A common side effect for these groups of drugs is their ability to prolong the QT interval and induce paroxysms of polymorphic ventricular tachycardia torsades de pointes, especially in patients with genetic defects of ventricular myocardial repolarization. This article provides management algorithms of COVID-19 in patients with QT interval prolongation and risk of life-threatening ventricular arrhythmias, developed with the support of the EurAsian Arrhythmology Association (EURA-3).

2020

hydroxychloroquine, QT interval, coronavirus disease (covid-19), polymorphic ventricular tachycardia torsades de pointes

DOI: 10.25298/2221-8785-2020-18-2-203-210

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta

Grodno State Medical University

Medicine