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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Coronavirus</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Dominio científico: Coronavirus</text>
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          <name>Title</name>
          <description>A name given to the resource</description>
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              <text>Feline Coronavirus 3c Protein: A Candidate for a Virulence Marker?</text>
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          <name>Creator</name>
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              <text>A. S. Hora, P. O. Tonietti, S. A. Taniwaki, K. M. Asano, P. Maiorka, L. J. Richtzenhain, P. E. Brandão</text>
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              <text>Feline infectious peritonitis virus (FIPV) is highly virulent and responsible for the highly fatal disease feline infectious peritonitis (FIP), whereas feline enteric coronavirus (FECV) is widespread among the feline population and typically causes asymptomatic infections. Some candidates for genetic markers capable of differentiating these two pathotypes of a unique virus (feline coronavirus) have been proposed by several studies. In the present survey, in order to search for markers that can differentiate FECV and FIPV, several clones of the 3a–c, E, and M genes were sequenced from samples obtained from cats with or without FIP. All genes showed genetic diversity and suggested the presence of FCoV mutant spectrum capable of producing a virulent pathotype in an individual-specific way. In addition, all the feline coronavirus FIPV strains demonstrated a truncated 3c protein, and the 3c gene was the only observed pathotypic marker for FCoVs, showing that 3c gene is a candidate marker for the distinction between the two pathotypes when the mutant spectrum is taken into account.</text>
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          <name>Date</name>
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              <text>2016</text>
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          <name>Identifier</name>
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              <text>DOI: 10.1155/2016/8560691</text>
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          <name>Source</name>
          <description>A related resource from which the described resource is derived</description>
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              <text>BioMed Research International</text>
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          <name>Publisher</name>
          <description>An entity responsible for making the resource available</description>
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              <text>Hindawi Limited</text>
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          </elementTextContainer>
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          <name>Coverage</name>
          <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <text>Medicine</text>
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