https://www.socictopen.socict.org/files/original/6e7ce0b02c44496210ad3fd310724b07.pdf 341e2d25e9c6ce3b5b806f461739260e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels Creator An entity primarily responsible for making the resource Vienna R. Brown, Danielle R. Adney, Richard A. Bowen, Emmie de Wit, Dana Scott, Neeltje van Doremalen, Trenton Bushmaker, Vincent J. Munster Description An account of the resource In 2012, a novel coronavirus associated with severe respiratory disease in humans emerged in the Middle East. Epidemiologic investigations identified dromedary camels as the likely source of zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Here we provide experimental support for camels as a reservoir for MERS-CoV. We inoculated 3 adult camels with a human isolate of MERS-CoV and a transient, primarily upper respiratory tract infection developed in each of the 3 animals. Clinical signs of the MERS-CoV infection were benign, but each of the camels shed large quantities of virus from the upper respiratory tract. We detected infectious virus in nasal secretions through 7 days postinoculation, and viral RNA up to 35 days postinoculation. The pattern of shedding and propensity for the upper respiratory tract infection in dromedary camels may help explain the lack of systemic illness among naturally infected camels and the means of efficient camel-to-camel and camel-to-human transmission. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource inoculation, coronavirus, camels, MERS-CoV, Middle East respiratory syndrome, Dromedary Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2012.141280 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine