SARS-CoV-2 / COVID-19 and its Transmission, Prevention, Treatment and Control - An Update

SARS-CoV-2 / COVID-19 and its Transmission, Prevention, Treatment and Control - An Update

Pooja Sharma, Kuldeep Dhama, Ram Chandra, Sonam Tripathi, Shailesh Kumar Patel

Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Virus-2 (SARSCoV-2), pandemic has caused huge panic, havoc and global threats worldwide. The origin of this virushas been linked to animals, intermediate host is still to be identified, and studies are being carried outthat how it got transmitted to humans and acquired rapid human-to-human transmission. Within ashort time period of only 05 months, SARS-CoV-2 has spread to 213 countries, and till 28th May, 2020,nearly 5.8 million confirmed cases have been reported while taking lives of 0.36 million persons. Seeingthe current situation of rapid increase in COVID-19 cases daily in many countries, this seems to be thedeadliest pandemic after the 1918 Spanish Flu. There is currently no specific effective treatment forCOVID-19 and also in absence of vaccine the radical cure of the disease is far away. Researchers arepacing high to design and develop effective vaccines, drugs and therapeutics to counter COVID-19,however such efforts, clinical trials, necessary approvals and then to reach the level of bulk productionof many millions of doses may still take much time. Prevention and control of COVID-19 outbreaksrequires an evidence-based, multi-factorial and effective mitigation strategy to be adopted. The currentreview discusses on the research advancements, challenges and opportunities in COVID 19 managementwith a focus on its transmission, prevention, treatment and control.

2020

prevention, treatment, control, Transmission, SARS-CoV-2, COVID-19

DOI: 10.22207/JPAM.14.SPL1.32

Journal of Pure and Applied Microbiology

Journal of Pure and Applied Microbiology

Microbiology