Distribution of COVID-19 and Phylogenetic Tree Construction of SARS-CoV-2 in Indonesia

Distribution of COVID-19 and Phylogenetic Tree Construction of SARS-CoV-2 in Indonesia

Arif Nur Muhammad Ansori, Dora Dayu Rahma Turista, Viol Dhea Kharisma, Aesthetica Islamy

Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndromecoronavirus 2 (SARS-CoV-2). COVID-19 has spread quickly across the world and has been declareda pandemic. Indonesia has many COVID-19 cases, with a high mortality rate. This study aimed todescribe the distribution of COVID-19 in Indonesia and constructed the SARS-CoV-2 phylogenetictree from Indonesian isolates and those from other countries, including other CoVs to determinetheir relationship. The distribution data of COVID-19 in Indonesia were obtained from the COVID-19Management Handling Unit and descriptively analyzed. SARS-CoV-2 isolates were retrieved from theGenBank® (National Center of Biotechnology Information, USA) and GISAID EpiCoV™ databases andwere used to construct phylogenetic trees using MEGA X software. Of the 37 provinces in Indonesia,five provinces with the highest case fatality rates were DKI Jakarta, Jawa Barat, Jawa Timur, and Banten,and the five provinces with the highest cure rate were Kepulauan Riau, Bali, Aceh, Gorontalo, and DIYogyakarta. SARS-CoV-2 Indonesian isolates were closely related to SARS-CoV-2 isolates from othercountries. The rapid and widespread distribution of SARS-CoV-2 in Indonesia was caused by the lackof compliance with territorial restrictions and dishonesty with medical personnel. These data revealedthat mutations can occur during the transmission process, which can be caused by a history of traveland increased patient immunity.

2020

Indonesia, phylogenetic tree, SARS-CoV-2, COVID-19

DOI: 10.22207/JPAM.14.SPL1.42

Journal of Pure and Applied Microbiology

Journal of Pure and Applied Microbiology

Microbiology