Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer's Disease.

Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer's Disease.

Natalia Soldevila-Domenech, Laura Forcano, Anna Boronat, Thais Lorenzo, Iris Piera, Albert Puig-Pijoan, Julian Mateus, José María González de Echevarri Gómez, Iva Knezevic, Anna Soteras, Karine Fauria, Nieves Pizarro, Jose Luis Molinuevo, Rafael de la Torre

We explored the impact of the Spanish COVID-19 strict home confinement on mental health and cognition in non-infected subjects (N = 16, 60-80 years) diagnosed with subjective cognitive decline and APOEɛ3/ɛ4 carriers. Mental health was monitored for 2 months on a daily, weekly, or monthly basis, and compared to pre-confinement values. Emotional distress, anxiety, and depression scores increased to pathological threshold values during and after confinement. Those with lower mood during confinement experienced a decline in their mood after confinement. Cognition did not change. These preliminary results suggest that mental health consequences of corona measures in preclinical stages of Alzheimer's disease should be further evaluated.

2021

mental health, covid-19, Confinement, Alzheimer’s disease, subjective cognitive decline

10.3233/JAD-201408

Journal of Alzheimer's disease : JAD