https://www.socictopen.socict.org/files/original/8f40d94c24057135e0f89477a8962fe1.pdf 642582be898b1c7cbf09aeae48ccae5c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses Creator An entity primarily responsible for making the resource Víctor M González, M Elena Martín, Gerónimo Fernández, Ana García-Sacristán Description An account of the resource Appropriate diagnosis is the key factor for treatment of viral diseases. Time is the most important factor in rapidly developing and epidemiologically dangerous diseases, such as influenza, Ebola and SARS. Chronic viral diseases such as HIV-1 or HCV are asymptomatic or oligosymptomatic and the therapeutic success mainly depends on early detection of the infective agent. Over the last years, aptamer technology has been used in a wide range of diagnostic and therapeutic applications and, concretely, several strategies are currently being explored using aptamers against virus proteins. From a diagnostics point of view, aptamers are being designed as a bio-recognition element in diagnostic systems to detect viral proteins either in the blood (serum or plasma) or into infected cells. Another potential use of aptamers is for therapeutics of viral infections, interfering in the interaction between the virus and the host using aptamers targeting host-cell matrix receptors, or attacking the virus intracellularly, targeting proteins implicated in the viral replication cycle. In this paper, we review how aptamers working against viral proteins are discovered, with a focus on recent advances that improve the aptamers’ properties as a real tool for viral infection detection and treatment. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource aptamer, diagnosis, Ebola, HBV, HCV, HIV, influenza, SELEX, therapeutic, virus Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ph9040078 Source A related resource from which the described resource is derived Pharmaceuticals Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pharmacy and materia medica Language A language of the resource EN