Extracorporeal membrane oxygenation for severe Middle East respiratory syndrome coronavirus

Extracorporeal membrane oxygenation for severe Middle East respiratory syndrome coronavirus

Mohammed S. Alshahrani, Anees Sindi, Fayez Alshamsi, Awad Al-Omari, Mohamed El-Tahan, Bayan Alahmadi, Ahmed Zein, Naif Khatani, Fahad Al Hameed, Sultan Alamri, Mohammed Abdelzaher, Amenah Alghamdi, Faisal Alfousan, Adel Tash, Wail Tashkandi, Rajaa Al-Raddadi, Kim Lewis, Mohammed Badawee, Yaseen M. Arabi, Eddy Fan, Waleed Alhazzani

Abstract Background Middle East respiratory syndrome (MERS) is caused by a coronavirus (MERS‐CoV) and is characterized by hypoxemic respiratory failure. The objective of this study is to compare the outcomes of MERS-CoV patients before and after the availability of extracorporeal membrane oxygenation (ECMO) as a rescue therapy in severely hypoxemic patients who failed conventional strategies. Methods We collected data retrospectively on MERS-CoV patients with refractory respiratory failure from April 2014 to December 2015 in 5 intensive care units (ICUs) in Saudi Arabia. Patients were classified into two groups: ECMO versus conventional therapy. Our primary outcome was in-hospital mortality; secondary outcomes included ICU and hospital length of stay. Results Thirty-five patients were included; 17 received ECMO and 18 received conventional therapy. Both groups had similar baseline characteristics. The ECMO group had lower in-hospital mortality (65 vs. 100%, P = 0.02), longer ICU stay (median 25 vs. 8 days, respectively, P 

2018

Coronavirus infection, extracorporeal membrane oxygenation, Rescue therapy, Signs and symptoms respiratory

DOI: 10.1186/s13613-017-0350-x

Annals of Intensive Care

SpringerOpen

Medical emergencies. Critical care. Intensive care. First aid

EN