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                <text>Coronavirus</text>
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                <text>Dominio científico: Coronavirus</text>
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              <text>Perspectivas imunoterapêuticas para COVID-19</text>
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              <text>Lucas Gomes de Hollanda Cavalcanti, Luciana Xavier Oliveira, Melina Pezzo Bustamante, Marileia Chaves Andrade</text>
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              <text>Com o surgimento da COVID-19, iniciou-se uma constante pesquisa sobre a infecção pelo SARS-CoV-2 e suas perspectivas terapêuticas. Com evidente contribuição da atividade imunológica na patogênese da COVID-19, destacam-se as principais perspectivas imunoterapêuticas em desenvolvimento. Ainda, se investiga o envolvimento da neutrofilia e da formação de Neutrophil Extracellular Traps (NETs) no agravamento do quadro clínico. Portanto, acredita-se que controlar atividade de neutrófilos e a formação de NETs seja um dos caminhos para atenuar a gravidade da doença. Outra proposta é a administração de plasma convalescente ou imunoglobulina (IgG) intravenosa, que neutralizariam a entrada do vírus nas células e modularia a resposta imune. No entanto, os tratamentos ainda não são definitivos e carecem de resultados favoráveis.</text>
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              <text>covid-19, SARS-CoV-2, Imunologia, imunoterapia</text>
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              <text>Epidemiology and Health</text>
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              <text>Korean Society of Epidemiology</text>
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              <text>Medicine (General), Nursing</text>
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