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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Coronavirus</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Dominio científico: Coronavirus</text>
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          <name>Title</name>
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              <text>EFEITO DO EXTRATO AQUOSO DE PRÓPOLIS MARROM SOBRE A PRODUÇÃO DE IFN-γ APÓS IMUNIZAÇÃO CONTRA PARVOVÍRUS CANINO (CPV) E CORONAVÍRUS CANINO (CCoV)</text>
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          <name>Creator</name>
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              <text>Maureen Hoch Vieira Fernandes, Lílian das Neves Ferreira, Gilberto D'Ávila Vargas, Geferson Fischer, Silvia de Oliveira Hübner</text>
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              <text>The purpose of this study was to evaluate the imunnostimulatory adjuvant capacity of water extract from brown propolis (WEBP) when added to a vaccine against canine parvovirus (CPV) and canine coronavirus (CCoV), regarding the production of IFN-γ. Mice were vaccinated with CPV and CCoV (3.0 x 106 TCID50) with or without 400 µg/dose of WEBP. Thirty days after the third dose, splenocytes were cultured to measure the expression levels of IFN-γ mRNA in the immunized animals. Increased levels of IFN-γ mRNA expression for CCoV were evidenced by RT-PCR, in the splenocytes of mice inoculated with the vaccine containing 400 μg/dose of WEBP, demonstrating the ability of propolis to stimulate cellular immune responses against the antigens of this virus. In contrast, the levels of IFN-γ to CPV were not influenced by the presence of WEBP.</text>
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              <text>2015</text>
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          <name>Subject</name>
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              <text>adjuvant, canine coronavirus, canine parvovirus, vaccine</text>
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          <name>Identifier</name>
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              <text>DOI: 10.1590/1089-6891v16i223458</text>
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          <name>Source</name>
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              <text>Ciência Animal Brasileira</text>
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          <name>Publisher</name>
          <description>An entity responsible for making the resource available</description>
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            <elementText elementTextId="5993">
              <text>Universidade Federal de Goiás</text>
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          <name>Coverage</name>
          <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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            <elementText elementTextId="5994">
              <text>Agriculture, Animal culture</text>
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          <name>Language</name>
          <description>A language of the resource</description>
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              <text>EN, PT</text>
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