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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Coronavirus</text>
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                <text>Dominio científico: Coronavirus</text>
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              <text>The prognostic role of cardiac troponin in hospitalized COVID-19 patients.</text>
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              <text>Osman Çelik, Naim Ata, Ibrahim Halil Tanboğa, Uğur Canpolat, Elif Hande Özcan Çetin, Harun Kundi, Sema Turan, Serkan Çay, Özcan Özeke, Cihangir Kaymaz, Serkan Topaloğlu</text>
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              <text>Myocardial injury defined by elevation of cardiac troponins (cTn) in the course of coronavirus disease 2019 (COVID-19) pandemic has been reported, though not fully characterized yet. Using the Turkish nationwide centralized COVID-19 database, we sought to determine whether cTn measured within 24 h of admission may help identify 30-day all-cause mortality in hospitalized patients. This retrospective cohort study was conducted at all hospitals in Turkey between March 11, 2020, and June 22, 2020. All hospitalized COVID-19 patients (≥18 years) who had cTn measurements within 24 h of admission were included. The primary outcome was 30-day all-cause mortality. A total of 14,855 COVID-19 patients (median age 49 years and 54% male) from 81 provinces of Turkey were included. Of these, 2020 patients (13.6%) were transferred to intensive care unit, 1165 patients (7.8%) needed mechanical ventilation, and 882 patients (5.9%) died during hospitalization. The prevalence of cTn positivity was 6.9% (n = 1027) in the hospitalized patients. cTn positivity was 5% in those patients alive at 30-day, and 44% in those who died. In multivariable Cox proportional hazard regression model, age, lactate dehydrogenase, and cTn were the strongest predictors of 30-day mortality, irrespective of cTn definition as a continuous, ordinal variable, or dichotomic variables. A single measurement of cTn at admission in patients with COVID-19 is associated with 30-day all-cause mortality and may have an important prognostic role for optimizing risk stratification.</text>
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              <text>2021</text>
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          <name>Subject</name>
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              <text>mortality, covid-19, prognosis, troponin</text>
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              <text>10.1016/j.atherosclerosis.2021.04.006</text>
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          <name>Source</name>
          <description>A related resource from which the described resource is derived</description>
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              <text>Atherosclerosis</text>
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