https://www.socictopen.socict.org/files/original/1325cdc207494487a22095295b97d0e8.pdf a5b96ccf3065e2853a56ca4dc683a1c0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Mesenchymal stem cell infusion as a promising therapeutic approach to treat coronavirus disease 2019 patients Creator An entity primarily responsible for making the resource Nihal AlMuraikhi Description An account of the resource Coronavirus disease 2019 (COVID-19) is a highly contagious respiratory infection that emerges as a serious healthcare problem and becomes a global pandemic. The disease is caused by a novel virus called SARS-CoV-2. The initial site of infection is the pulmonary epithelial cells when the surface spike protein of the virus binds to their angiotensin I converting enzyme 2 receptor receptor triggering the immune system to release a huge number of inflammatory cytokines that may result in a cytokine storm. The clinical spectrum of the infections ranges from asymptomatic cases to severe viral pneumonia with multiple organ dysfunction that may lead to death. Currently, no specific antiviral drugs or vaccine has been confirmed to cure COVID-19. Mesenchymal stem cells (MSCs) present a potential therapeutic approach for treating COVID-19 patients through their regeneration of damaged tissues, anti-inflammatory, and immunomodulatory features. Preclinical data suggest that they can reduce pro-inflammatory cytokines, mitigate cytokine storm, and repair microenvironment of damaged tissues. MSCs are allogeneic stem cells that mainly get trapped in the lung when they are infused intravenously. Since the lung is the main affected organ in COVID-19 patients, this therapeutic approach seems to be advantageous. In this manuscript, we are describing this novel disease and its mechanism of infection, and stating the urgent need for treatment. Although many treatments are now being investigated for their effectiveness, this review has been dedicated to introducing all the supportive evidence in favor of utilizing the MSC therapy as a powerful therapeutic approach to improve the immunological response of COVID-19 patients. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Coronavirus disease 2019, Immunomodulation, cytokine storm, Mesenchymal stem cells, anti-inflammation, regeneration, angiotensin i-converting enzyme 2 receptor Identifier An unambiguous reference to the resource within a given context 10.4103/JNSM.JNSM_46_20 Source A related resource from which the described resource is derived Journal of Nature and Science of Medicine Publisher An entity responsible for making the resource available Wolters Kluwer Medknow Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine, Public aspects of medicine