https://www.socictopen.socict.org/files/original/5ddaf2652d0b4120ff1769556c37d9f8.pdf 39debffdcbbe19666d5f40a91bde68dc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COVID-19: Integrating the Complexity of Systemic and Pulmonary Immunopathology to Identify Biomarkers for Different Outcomes Creator An entity primarily responsible for making the resource Thais Fernanda de Campos Fraga-Silva, Thais Fernanda de Campos Fraga-Silva, Sandra Regina Maruyama, Carlos Arterio Sorgi, Elisa Maria de Sousa Russo, Ana Paula Morais Fernandes, Cristina Ribeiro de Barros Cardoso, Cristina Ribeiro de Barros Cardoso, Lucia Helena Faccioli, Lucia Helena Faccioli, Marcelo Dias-Baruffi, Vânia Luiza Deperon Bonato, Vânia Luiza Deperon Bonato Description An account of the resource In the last few months, the coronavirus disease 2019 (COVID-19) pandemic has affected millions of people worldwide and has provoked an exceptional effort from the scientific community to understand the disease. Clinical evidence suggests that severe COVID-19 is associated with both dysregulation of damage tolerance caused by pulmonary immunopathology and high viral load. In this review article, we describe and discuss clinical studies that show advances in the understanding of mild and severe illness and we highlight major points that are critical for improving the comprehension of different clinical outcomes. The understanding of pulmonary immunopathology will contribute to the identification of biomarkers in an attempt to classify mild, moderate, severe and critical COVID-19 illness. The interface of pulmonary immunopathology and the identification of biomarkers are critical for the development of new therapeutic strategies aimed to reduce the systemic and pulmonary hyperinflammation in severe COVID-19. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource Coronavirus disease 2019, Pulmonary inflammation, damage tolerance, Peripheral immune response, lung immunopathology Identifier An unambiguous reference to the resource within a given context 10.3389/fimmu.2020.599736 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Immunologic diseases. Allergy