https://www.socictopen.socict.org/files/original/3a4ca1b703cb9f5888a0a07d1b713de6.pdf 805abe8ad314b4696a7b223f7a30fd3c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Topographic Changes in SARS Coronavirus–infected Cells during Late Stages of Infection Creator An entity primarily responsible for making the resource Mah-Lee Ng, J.W.M. Lee, M.L.N. Leong, A.-E. Ling, H.-C. Tan, E.E. Ooi Description An account of the resource Scanning electron and atomic force microscopy was used for the first time to view the maturation of the severe acute respiratory syndrome–associated coronavirus at the cell surface. The surface form of the cells at advanced infection displayed prolific pseudopodia that, in addition to the rest of the plasma membrane, were also active sites of virus release. High magnification of the maturing virus particles showed a rosette appearance with short knoblike spikes under both the scanning electron and atomic force microscopes. The final expulsion step of the maturing virus particles seemed to result in some disruptions to the plasma membrane. The cytoskeletal network along the edge of the infected cells was enhanced and could be involved in transporting and expelling the progeny virus particles. Thickening of the actin filaments at the cell edge provided the bending force to extrude the virus particles. Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource SARS coronavirus replication, Atomic Force Microscopy, scanning electron microscopy, research, Singapore Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1011.040195 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN