https://www.socictopen.socict.org/files/original/00017d8dea85c83c40485360a9705ff7.pdf 172ad2e583abe668e2977811994433fa Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Intranasal DNA Vaccine for Protection against Respiratory Infectious Diseases: The Delivery Perspectives Creator An entity primarily responsible for making the resource Yingying Xu, Pak-Wai Yuen, Jenny Ka-Wing Lam Description An account of the resource Intranasal delivery of DNA vaccines has become a popular research area recently. It offers some distinguished advantages over parenteral and other routes of vaccine administration. Nasal mucosa as site of vaccine administration can stimulate respiratory mucosal immunity by interacting with the nasopharyngeal-associated lymphoid tissues (NALT). Different kinds of DNA vaccines are investigated to provide protection against respiratory infectious diseases including tuberculosis, coronavirus, influenza and respiratory syncytial virus (RSV) etc. DNA vaccines have several attractive development potential, such as producing cross-protection towards different virus subtypes, enabling the possibility of mass manufacture in a relatively short time and a better safety profile. The biggest obstacle to DNA vaccines is low immunogenicity. One of the approaches to enhance the efficacy of DNA vaccine is to improve DNA delivery efficiency. This review provides insight on the development of intranasal DNA vaccine for respiratory infections, with special attention paid to the strategies to improve the delivery of DNA vaccines using non-viral delivery agents. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource DNA vaccine, Intranasal delivery, infectious diseases, respiratory pathogens, adjuvants, mucosal Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/pharmaceutics6030378 Source A related resource from which the described resource is derived Pharmaceutics Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pharmacy and materia medica Language A language of the resource EN