Development of Small-Molecule MERS-CoV Inhibitors

Development of Small-Molecule MERS-CoV Inhibitors

Ruiying Liang, Li-li WANG, Naru Zhang, Xiaoqian Deng, Meng SU, Yudan Su, Lanfang Hu, Chen He, Tianlei Ying, Shibo Jiang, Fei Yu

Middle East respiratory syndrome coronavirus (MERS-CoV) with potential to cause global pandemics remains a threat to the public health, security, and economy. In this review, we focus on advances in the research and development of small-molecule MERS-CoV inhibitors targeting different stages of the MERS-CoV life cycle, aiming to prevent or treat MERS-CoV infection.

2018

MERS-CoV, mechanism of action, Small molecule inhibitor

DOI: 10.3390/v10120721

Viruses

MDPI AG

Microbiology

EN