https://www.socictopen.socict.org/files/original/38d3b55cc7835c1bd35c3aef966635ea.pdf 150a9e39296bef2277af704afd565854 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Application of newly developed SARS-CoV2 serology test along with real-time PCR for early detection in health care workers and on-time plasma donation. Creator An entity primarily responsible for making the resource Hossein Samadi Kafil, Leila Roshangar, Leili Aghebati-Maleki, Mahsa Hajivalili, Ata Mahmoodpoor, Javad Ahmadian Heris, Maryam Hosseini, Mehdi Yousefi, Mohammad Sadegh Soltani-Zangbar, Mostafa Haji-Fatahaliha, Roza Motavalli, Sara Farhang, Ramin Pourakbari, Farhad Jadidi-Niaragh, Amin Kamrani, Homayoon Siahmansouri, Abolfazl Miahipour, Oldouz Shareghi-Oskoue, Forough Parhizkar Description An account of the resource As the daily number of coronavirus infection disease 19 (COVID19) patients increases, the necessity of early diagnosis becomes more obvious. In this respect, we aimed to develop a serological test for specifically detecting anti-SARS-CoV2 antibodies. We collected serum and saliva samples from 609 individuals who work at TBZMED affiliated hospitals in Tabriz, Iran, from April to June of 2020. Real-time PCR technique was used to detect SARS-CoV-2 genome using specific primers. An enzyme linked immunosorbent assay (ELISA) test was designed based on virus nucleocapsid (N), spike (S) and its receptor binding domain (RBD) protein, and the collected sera were subjected to IgM and/or IgG analysis. Real-time PCR results showed that 66 people were infected with the SARS-CoV-2. Our designed ELISA kit showed 93.75% and 98% of sensitivity and specificity, respectively. In this study, 5.74% of participants had specific IgG against RBD, whereas the percentage for IgM positive individuals was 5.58%. Approximately the same results were observed for S protein. The number of positive participants for NP increased further, and the results of this antigen showed 7.38% for IgG and 7.06% for IgM. The ELISA test beside real-time PCR could provide a reliable serologic profile for the status of the disease progress and early detection of individuals. More importantly, it possesses the potential to identify the best candidates for plasma donation according to the antibody titers. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource ELISA, spike protein, Nucleocapsid protein, receptor-binding domain, SARS-CoV-2, IgG, IgM, RBD, receptor binding domain, PCR, polymerase chain reaction, N, Nucleocapsid protein, S, Spike protein, ELISA, enzyme-linked immune-sorbent assay, SARS-CoV-2, Severe Acute Respiratory Syndrome caused by Coronavirus-2 Identifier An unambiguous reference to the resource within a given context 10.1016/j.genrep.2021.101140 Source A related resource from which the described resource is derived Gene reports