COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions.

COVID-19 and hyperammonemia: Potential interplay between liver and brain dysfunctions.

Larissa Daniele Bobermin, André Quincozes-Santos

Although COVID-19 affects the respiratory system, extrapulmonary manifestations frequently occur, including encephalopathy and liver damage. Here, we want to call attention to a possible connection between liver and brain dysfunctions, in which ammonia can play a role targeting astrocytes. Importantly, astrocyte dysfunction can produce future and/or long-term neurological consequences.

2021

covid-19, ammonia, Liver dysfunction, astrocytes, Brain dysfunction

10.1016/j.bbih.2021.100257

Brain, behavior, & immunity - health