COVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone system
Título
COVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone system
Autor
Susanne Rysz, Francesca Campoccia Jalde, Johan Lundberg, Malin Jonsson Fagerlund, Sven Nyrén, Tobias Granberg, Jonathan Al-Saadi, Anna Sjöström, Maria Farm, Michael Plattén, Helen Eriksson, Margareta Klein, Roberto Vargas-Paris, Goran Abdula, Russell Ouellette
Descripción
The SARS-CoV-2 receptor ACE2 is involved in the Renin-Angiotensin-Aldosterone System (RAAS). Over-activation of RAAS in swine results in a disease state similar to that of COVID-19 in human patients, suggesting that COVID-19 pathophysiology may be driven, at least in part, by an imbalance of this hormonal system.
Fecha
2021
Identificador
10.1038/s41467-021-22713-z
Fuente
Epidemiology and Health
Editor
Korean Society of Epidemiology
Cobertura
Science
Archivos
Colección
Citación
Susanne Rysz, Francesca Campoccia Jalde, Johan Lundberg, Malin Jonsson Fagerlund, Sven Nyrén, Tobias Granberg, Jonathan Al-Saadi, Anna Sjöström, Maria Farm, Michael Plattén, Helen Eriksson, Margareta Klein, Roberto Vargas-Paris, Goran Abdula, Russell Ouellette, “COVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone system,” SOCICT Open, consulta 18 de abril de 2026, https://www.socictopen.socict.org/items/show/9214.
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