Marked Sinus Bradycardia Associated With Remdesivir in COVID-19: A Case and Literature Review.

Marked Sinus Bradycardia Associated With Remdesivir in COVID-19: A Case and Literature Review.

James C Gubitosa, Parul Kakar, Christine Gerula, Hernando Nossa, Diana Finkel, Kristin Wong, Megna Khatri, Hasan Ali

Remdesivir has seen extensive use during the coronavirus disease-2019 pandemic given its clinically proven efficacy against severe acute respiratory syndrome coronavirus type 2. There has been little cited regarding adverse effects. Here we present the case of a patient with marked sinus bradycardia that began acutely on initiation of remdesivir and resolved almost immediately on cessation of the drug. (Level of Difficulty: Beginner.).

2020

cancer, cardiovascular disease, electrocardiogram, electrophysiology, COVID-19 (coronavirus disease 2019), Chest pain, Bradycardia, Physical examination, ECG, electrocardiogram, AV, atrioventricular, LBBB, left bundle branch block, h-mtRNAP, human mitochondrial RNA polymerase, lethargy, shortness of breath

10.1016/j.jaccas.2020.08.025

JACC. Case reports