https://www.socictopen.socict.org/files/original/eb14b0f79ee283f098947d976f5e8e4e.pdf cc733c80001273688dc5b07cbcdbe48e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Factors increasing the risk of mortality and morbidity due to coronavirus infection in patients with metabolic syndrome Creator An entity primarily responsible for making the resource Chang-Woo Lee, Altansuvd Enkhtur, Joon-Sup Yoon Description An account of the resource Patients living with comorbid metabolic syndrome (MS) and metabolic disorders such as obesity and type 2 diabetes mellitus carry increased levels of circulating cytokines and systemic low-grade inflammation. Upon viral infection, such patients with all pre-existing backgrounds, specifically dysregulated inflammatory signalling, leads to rapid viral replication and results in worse clinical outcomes. The increased pro-inflammatory cytokine release is a risk factor, and therefore, targeting inflammatory signalling pathways represents a potential therapeutic target to control the cytokine release, and thereby prevent serious outcomes, such as increased mortality and morbidity. In this review, we elucidate the factors underlying the increased morbidity and mortality in patients with MS and virus infection, particularly coronavirus. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource inflammation, covid-19, metabolic syndrome, STAT transcription factors, JAK kinases Identifier An unambiguous reference to the resource within a given context 10.23838/pfm.2020.00121 Source A related resource from which the described resource is derived Precision and Future Medicine Publisher An entity responsible for making the resource available Sungkyunkwan University School of Medi Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine