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Impact of the state of emergency enacted due to the COVID-19 pandemic on the physical activity of the elderly in Japan.
[Purpose] In Japan, the government issued a state of emergency due to the spread of COVID-19 in April 2020. In this study, we measured physical activity before and after the state of emergency, and assessed the factors that affected physical…
Position: 3121 (43 views)
CORONAVIRUS DISEASE (COVID-19) TREATMENT ALGORITHMS IN PATIENTS WITH QT INTERVAL PROLONGATION
Since the frst cases of coronavirus disease (COVID-19) have been identifed, the search for effective drugs forits treatment has not stopped. The most promising in the treatment of COVID-19 are antimalarial, antiretroviraldrugs and macrolide…
Position: 15162 (20 views)
COVID-19 guidelines for optometry and optical services post-lockdown
The COVID-19 pandemic has caused disruption in everyone's lives globally. Optometrists, being primary health care professionals are at a higher risk of infection in their practices during these testing times. Optometrists and optical store owners…
Position: 11179 (24 views)
An Overview of COVID -19 and Dental Treatment Options
Objective: The aim of this article is to analyze the epidemiology of COVID-19, comparison of routes of transmission in children and adults, comparing the clinical symptoms in adults and children, dental protocol to be followed and possible dental…
Position: 15162 (20 views)
Use of the informational spectrum methodology for rapid biological analysis of the novel coronavirus 2019-nCoV: prediction of potential receptor, natural reservoir, tropism and therapeutic/vaccine target [version 3; peer review: 2 approved]
A novel coronavirus recently identified in Wuhan, China (SARS-CoV-2) has expanded the number of highly pathogenic coronaviruses affecting humans. The SARS-CoV-2 represents a potential epidemic or pandemic threat, which requires a quick response for…
Position: 14100 (21 views)
Novel SARS-CoV-2 Variant Derived from Clade 19B, France
We report a novel severe acute respiratory syndrome coronavirus 2 variant derived from clade 19B (HMN.19B variant or Henri Mondor variant). This variant is characterized by the presence of 18 amino acid substitutions, including 7–8 substitutions in…
Position: 7399 (29 views)
Approaches to the Management of Hypertension in Resource-Limited Settings: Strategies to Overcome the Hypertension Crisis in the Post-COVID Era
Jamario Skeete,1 Kenneth Connell,2 Pedro Ordunez,3 Donald J DiPette4 1Division of Cardiology, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA; 2Faculty of Medical Sciences, University of the West Indies, Cave Hill…
Position: 8738 (27 views)
Insights into the Immunopathophysiology of Severe COVID-19 in Metabolic Disorders
Coronavirus disease 2019 (COVID-19) has affected millions of people across the world but disproportionately and severely affects persons with metabolic disorders such as obesity, diabetes mellitus, and hypertension. In this brief review, we discuss…
Position: 4912 (35 views)
Rare mutations in the accessory proteins ORF6, ORF7b, and ORF10 of the SARS-CoV-2 genomes.
A total number of 3080 SARS-CoV-2 genomes from all continents are considered from the NCBI database. Every accessory protein ORF6, ORF7b, and ORF10 of SARS-CoV-2 possess a single missense mutation in less than 1.5% of the 3080 genomes. It has now…
Position: 17850 (17 views)
Pathogenic perspective of missense mutations of ORF3a protein of SARS-CoV-2.
One of the most important proteins for COVID-19 pathogenesis in SARS-CoV-2 is the ORF3a which is the largest accessory protein among others coded by the SARS-CoV-2 genome. The major roles of the protein include virulence, infectivity, ion channel…
Position: 19230 (15 views)