Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism

Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism

Craig Schindewolf, Vineet D. Menachery

Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines.

2019

Middle East respiratory syndrome coronavirus, severe acute respiratory syndrome coronavirus, coronavirus spike glycoprotein, vaccine platforms, correlates of immunity, animal models

DOI: 10.3390/v11010074

Viruses

MDPI AG

Microbiology

EN