A brief note on randomized controlled trials and compassionate/off-label use of drugs in the early phases of the COVID-19 pandemic
Título
A brief note on randomized controlled trials and compassionate/off-label use of drugs in the early phases of the COVID-19 pandemic
Autor
Paolo Pelosi, Matteo Bassetti, Antonio Vena, Chiara Robba, Daniele Roberto Giacobbe
Descripción
Randomized controlled trials (RCTs) are the best way to find effective and acceptable safe treatments for COVID-19 and any possible future outbreak. However, caution is needed when comparing the number of participants in RCTs with that of patients with COVID-19 treated with compassionate and/or off-label drugs to support the hypothesis that the latter are preferred by clinicians as an alternative to the former.
Fecha
2020
Materia
coronavirus, RCT, off-label, Compassionate, SARS-CoV-2, COVID-19
Identificador
DOI: 10.7573/dic.2020-5-2
Fuente
Drugs in Context
Editor
BioExcel Publishing Ltd
Cobertura
Therapeutics. Pharmacology
Archivos
Colección
Citación
Paolo Pelosi, Matteo Bassetti, Antonio Vena, Chiara Robba, Daniele Roberto Giacobbe, “A brief note on randomized controlled trials and compassionate/off-label use of drugs in the early phases of the COVID-19 pandemic,” SOCICT Open, consulta 18 de abril de 2026, https://www.socictopen.socict.org/items/show/3406.
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