Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States.
Título
Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States.
Autor
Chantal B F Vogels, Anne E Watkins, Jianhui Wang, Chaney C Kalinich, Joseph R Fauver, Pei Hui, Chen Liu, Mallery I Breban, Tara Alpert, Mary E Petrone, Gaurav Khullar, Jessica Metti, Joel T Dudley, Matthew J MacKay, Megan Nash, Anthony Muyombwe, Randy Downing, Jafar Razeq, Anderson F Brito, Erica Lasek-Nesselquist, Jessica Rothman, Andrew L Valesano, Simon Dellicour, Alexis Russell, John P Kelly, Matthew Shudt, Jonathan Plitnick, Erasmus Schneider, William J Fitzsimmons, Nike Beaubier, Stephen M Bart, Ardath Grills, Stephanie M Morrison, Steven Murphy, Caleb Neal, Eva Laszlo, Hanna Rennert, Melissa Cushing, Lars Westblade, Priya Velu, Arryn Craney, Lin Cong, David R Peaper, Marie L Landry, Peter W Cook, Christopher E Mason, Adam S Lauring, Kirsten St George, Duncan R MacCannell, Nathan D Grubaugh
Descripción
The emergence and spread of SARS-CoV-2 lineage B.1.1.7, first detected in the United Kingdom, has become a global public health concern because of its increased transmissibility. Over 2,500 COVID-19 cases associated with this variant have been detected in the United States (US) since December 2020, but the extent of establishment is relatively unknown. Using travel, genomic, and diagnostic data, we highlight that the primary ports of entry for B.1.1.7 in the US were in New York, California, and Florida. Furthermore, we found evidence for many independent B.1.1.7 establishments starting in early December 2020, followed by interstate spread by the end of the month. Finally, we project that B.1.1.7 will be the dominant lineage in many states by mid- to late March. Thus, genomic surveillance for B.1.1.7 and other variants urgently needs to be enhanced to better inform the public health response.
Fecha
2021
Materia
epidemiology, Phylogenetics, SARS-CoV-2, community transmission, variant, B.1.1.7, genomic surveillance, lineage, flight volumes, introductions
Identificador
10.1016/j.cell.2021.03.061
Fuente
Cell
Archivos
Colección
Citación
Chantal B F Vogels, Anne E Watkins, Jianhui Wang, Chaney C Kalinich, Joseph R Fauver, Pei Hui, Chen Liu, Mallery I Breban, Tara Alpert, Mary E Petrone, Gaurav Khullar, Jessica Metti, Joel T Dudley, Matthew J MacKay, Megan Nash, Anthony Muyombwe, Randy Downing, Jafar Razeq, Anderson F Brito, Erica Lasek-Nesselquist, Jessica Rothman, Andrew L Valesano, Simon Dellicour, Alexis Russell, John P Kelly, Matthew Shudt, Jonathan Plitnick, Erasmus Schneider, William J Fitzsimmons, Nike Beaubier, Stephen M Bart, Ardath Grills, Stephanie M Morrison, Steven Murphy, Caleb Neal, Eva Laszlo, Hanna Rennert, Melissa Cushing, Lars Westblade, Priya Velu, Arryn Craney, Lin Cong, David R Peaper, Marie L Landry, Peter W Cook, Christopher E Mason, Adam S Lauring, Kirsten St George, Duncan R MacCannell, Nathan D Grubaugh, “Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States.,” SOCICT Open, consulta 18 de abril de 2026, https://www.socictopen.socict.org/items/show/9203.
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